Peter Wallace has been ruled out with a minor neck injury suffered in last Sunday's game against Cronulla Sharks.
With Wallace sidelined, James Maloney will assume the captaincy of the Panthers and Sione Katoa will start at hooker. 21-year-old Wayde Egan, who made his NRL debut against North Queensland in Round 4, earns a spot on the bench.
Panthers
1. Dylan EDWARDS
2. Christian CRICHTON
3. Corey HARAWIRA-NAERA
4. Dean WHARE
5. Dallin WATENE-ZELEZNIAK
6. Tyrone PEACHEY
7. James MALONEY (c)
8. Trent MERRIN
14. Sione KATOA
10. Reagan CAMPBELL-GILLARD
11. Viliame KIKAU
12. Isaah YEO
13. James FISHER-HARRIS
18. Wayde EGAN
15. Jack HETHERINGTON
16. Moses LEOTA
17. James TAMOU