Brailey suffered the injury in the Sharks loss to Manly, then bravely battled on in the game against the Storm, however after undergoing surgery and on doctor's advice, he will miss this week's game.
He is expected to be good to for the round 24 match with the Knights.
James Segeyaro has been elevated to the starting side in Brailey's absence, with Joseph Paulo likely to be used should the PNG international hooker need a spell at some stage during the game.
Paulo has filled in previously at hooker and spent considerable time in the position at Sharks training at both the Wednesday and Friday training sessions.
Otherwise, the Sharks team is as selected on Tuesday, Scott Sorensen in for the injured Wade Graham, with Kurt Capewell filling the utility role off the interchange bench.
The Sharks 17-man team is listed below
1- Valentine Holmes
2- Sosaia Feki
3- Jesse Ramien
4- Ricky Leutele
5- Josh Dugan
6- Matt Moylan
7- Chad Townsend
8- Andrew Fifita
15- James Segeyaro
10- Matt Prior
11- Luke Lewis
12- Scott Sorensen
13- Paul Gallen
Interchange
14- Kurt Capewell
16- Aaron Woods
17- Jayson Bukuya
18- Joseph Paulo